IncobotulinumtoxinA 50 Units | Wholesale Per Vial
From $138.00 / vial
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The original "naked toxin" - Xeomin's unique protein-free IncobotulinumtoxinA in a precision 50U vial for targeted single-zone treatments
Xeomin- 50U delivers the same IncobotulinumtoxinA formulation that made Xeomin the world's only protein-free, "naked" botulinum toxin neurotoxin - in a smaller vial engineered for precision targeted dosing. Free of complexing proteins, Xeomin 50U carries a theoretical advantage for patients who may be developing antibody resistance to protein-rich toxin preparations, while also providing the cost-efficiency of a right-sized vial for single-zone treatments.
Also see: Xeomin 100U | Official info: Xeomin.com
Xeomin (IncobotulinumtoxinA) is the world's only botulinum toxin type A formulation that is entirely free of complexing proteins. Unlike Botox, Dysport, and other neurotoxins that contain accessory proteins alongside the active toxin, Xeomin contains only the pure 150-kDa botulinum toxin molecule. This proprietary XTRACT Technology purification process removes all non-therapeutic proteins from the formulation, leaving only what works.
The 50U Xeomin vial provides all these advantages in a right-sized format for practitioners treating single zones - crow's feet, perioral lines, chin, brow, or micro-dosing protocols - without opening and wasting a full 100U vial.
| Product Name | Xeomin- 50U |
| Active Ingredient | IncobotulinumtoxinA (pure 150-kDa neurotoxin) |
| Formulation | Protein-free - zero complexing proteins (XTRACT Technology) |
| Vial Size | 50 units per vial |
| Manufacturer | Merz Aesthetics GmbH |
| FDA Approval | Glabellar lines in adults; approved also for upper limb spasticity and cervical dystonia |
| Storage | Room temperature up to 25C - no refrigeration needed until opened |
| Onset of Action | 3-5 days; full effect at 2 weeks |
| Duration | 3-4 months (typical) |
Pricing is subject to change. For licensed practitioners only.
Merz's proprietary XTRACT Technology removes all non-essential complexing proteins from the botulinum toxin type A complex. The resulting formulation contains only the pure, active 150-kDa neurotoxin. This makes Xeomin unique among all commercially available botulinum toxins globally.
Reconstitute the 50U lyophilized powder with 0.9% preservative-free sodium chloride. Typical dilution: 1.0 mL yields 5U/0.1 mL. Inject intramuscularly into the targeted zone - glabellar, lateral canthal, perioral, or other focal treatment areas - using fine-gauge needles.
IncobotulinumtoxinA enters the presynaptic nerve terminal and cleaves the SNAP-25 protein, blocking acetylcholine vesicle docking and fusion. This prevents neuromuscular transmission, selectively and reversibly relaxing the injected muscle.
Treated muscles soften visibly over days 3-5, reaching full effect at week 2. Results are maintained for 3-4 months. The 50U vial is ideally suited for targeted retreatment scheduling, matching dosing precision to exactly what is needed per zone.
Xeomin 50U is ideal for practitioners who favor the naked toxin advantage and want a right-sized vial for targeted focal treatments. It is especially suited for patients who have developed secondary non-responsiveness to protein-containing neurotoxins (Botox, Dysport), as the absence of complexing proteins theoretically reduces the risk of neutralizing antibody formation.
The 50U format eliminates waste when treating single zones (crow's feet, perioral lines, chin, brow lift) and supports micro-dosing and skin quality protocols.
See Important Safety Information below.
Yes - same IncobotulinumtoxinA formulation, same potency per unit, same XTRACT-purified protein-free composition. The 50U vial simply contains half the units, making it ideal for targeted single-zone treatments without wasting reconstituted product.
Xeomin's XTRACT Technology removes all complexing proteins (hemagglutinins, non-hemagglutinin proteins) from the botulinum toxin type A complex, leaving only the pure active 150-kDa neurotoxin molecule. Other neurotoxins (Botox, Dysport) retain these accessory proteins, which may contribute to antibody formation over repeated treatments. Xeomin's "naked" formulation theoretically reduces this risk.
Unlike Botox which requires refrigeration at 2-8C, Xeomin is stable at room temperature (up to 25C/77F) for up to 36 months before reconstitution. Once reconstituted, use within 24 hours and store at 2-8C. This room-temperature stability simplifies logistics and cold-chain management.
Xeomin uses a 1:1 unit conversion with Botox. If you typically inject 20U of Botox for crow's feet, you would also inject 20U of Xeomin. This 1:1 equivalence makes switching straightforward for experienced neurotoxin injectors familiar with Botox dosing protocols.
Xeomin 50U results typically last 3-4 months, consistent with Botox at equivalent dosing. Studies show comparable duration between Xeomin and Botox at 1:1 dosing. Individual variation occurs based on muscle mass, metabolism, treatment zone, and injection technique.
Full 100U vial - ideal for multi-zone treatments and high-volume practices
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Merz's CE-marked international brand - same naked toxin, trusted in 60+ countries
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Important Safety Information