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OnabotulinumtoxinA - Allergan
The gold standard - 20+ years of proven safety and precision results
From $267.00 / vial
DaxibotulinumtoxinA | Wholesale Per Vial
From $349.00 / vial
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The world's longest-lasting FDA-approved neurotoxin - results lasting 6 months or more in the majority of clinical trial patients
Daxxify (DaxibotulinumtoxinA-lanm) is Revance Therapeutics' breakthrough neurotoxin and the only botulinum toxin type A stabilized with a proprietary peptide exchange technology (PRTX) rather than human serum albumin. This innovation allows for a stable, pure formulation with an extended duration of action. In pivotal clinical trials, the majority of patients maintained a none or mild severity score at 6 months, making Daxxify the longest-lasting FDA-approved neurotoxin available.
Also see: Botox Cosmetic | Official info: Daxxify.com
Daxxify (DaxibotulinumtoxinA-lanm) represents a genuine innovation in neurotoxin science. Developed by Revance Therapeutics and FDA-approved in 2022, it is the first and only botulinum toxin type A stabilized with a proprietary peptide - the PRTX peptide excipient - rather than human serum albumin. This eliminates the need for blood-derived stabilizers and enables an extended tissue residence time unlike any other toxin on the market.
In the pivotal SAKURA clinical program, the majority of Daxxify patients maintained at least a none or mild glabellar severity score at 6 months - a benchmark no other FDA-approved neurotoxin has achieved. For patients who want fewer appointments and longer-lasting results, Daxxify is a category-defining solution.
| Product Name | Daxxify |
| Active Ingredient | DaxibotulinumtoxinA-lanm (Botulinum Toxin Type A) |
| Vial Size | 100 units per vial |
| Manufacturer | Revance Therapeutics |
| FDA Approval | 2022 (glabellar frown lines) |
| Onset of Action | 3-7 days; full effect at 2 weeks |
| Duration | 6+ months (median in SAKURA trials) |
| Stabilizer | PRTX peptide excipient (no human albumin) |
Initial muscle relaxation and visible softening of glabellar frown lines begin.
Full effect established. Frown lines are significantly smoothed with natural-looking softening.
The majority of patients maintained results at 6 months - a clinical milestone no other FDA-approved neurotoxin has matched.
Wholesale prices listed per vial.
Pricing is subject to change. For licensed practitioners only.
Your Sculptra NYC practitioner evaluates your glabellar muscle activity, existing line depth, and overall facial anatomy. A personalized injection plan is created to maximize the longevity and precision of your Daxxify treatment.
Daxxify is administered with fine-gauge needles into the corrugator and procerus muscles responsible for frown lines. The procedure takes 15-20 minutes. Units are dosed in the same manner as Botox, allowing a familiar experience for both practitioners and patients.
DaxibotulinumtoxinA blocks acetylcholine release at the neuromuscular junction. The PRTX peptide stabilizer enables the toxin to remain active at the injection site longer than any other currently approved neurotoxin, translating to results that last significantly beyond the 3-4 month window of traditional products.
With results lasting 6 months or more for most patients, many Daxxify patients need only 2 treatments per year instead of the 3-4 needed with shorter-acting neurotoxins. This offers significant long-term value for high-volume practices and frequent treatment patients.
Daxxify is ideal for adults with moderate to severe glabellar frown lines who want the maximum duration from their neurotoxin treatment. It is particularly well-suited for busy patients who prefer fewer appointments per year, and for those who have been satisfied with traditional neurotoxins but want results that simply last longer.
Practitioners also benefit from Daxxify in high-volume settings where patient satisfaction is tied to treatment frequency. Fewer retreatment cycles can mean higher patient retention and overall satisfaction scores.
A consultation with a licensed Sculptra NYC specialist is required to determine candidacy. See Important Safety Information below.
In the SAKURA 1 and SAKURA 2 pivotal trials, the majority of patients maintained a none or mild glabellar severity score at 6 months. Some patients experienced results lasting up to 9 months. This is significantly longer than the 3-4 months typical of Botox, Dysport, or Xeomin.
Yes. Daxxify received FDA approval in September 2022 after demonstrating both safety and efficacy in clinical trials. Its PRTX peptide stabilizer has been well-tolerated. Adverse events are similar to other neurotoxins and are generally mild and transient.
Both are botulinum toxin type A products approved for glabellar lines. Daxxify uses the same unit system as Botox and has a similar onset (3-7 days). The key difference is duration: Daxxify lasts roughly 6 months in most patients versus 3-4 months for Botox. Daxxify is also stabilized with a peptide rather than human albumin.
Yes. Daxxify treats dynamic glabellar lines while fillers like Juvederm or Sculptra PLLA address volume loss and static wrinkles. Combining Daxxify's extended duration with a collagen stimulator like Sculptra creates a comprehensive, long-lasting facial rejuvenation protocol.
No significant downtime. Most patients return to normal activities immediately. Minor injection site reactions (redness, swelling) typically resolve within 30 minutes. Avoid strenuous exercise, lying flat, and touching treated areas for 4 hours after the procedure.

The gold standard - 20+ years of proven safety and precision results
From $267.00 / vial
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Important Safety Information