PCL Collagen Stimulator - 1 to 4 Years

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Polycaprolactone (PCL) | Immediate + Progressive Results | Select Formulation Below

From $380.00 / syringe

4.8 / 5.0 - 176 reviews

Ellans-S (Short) - 1mL~1 year longevity - ideal for first-time patients or areas requiring shorter correction

$380.00

Ellans-M (Medium) - 1mL~2 years longevity - most popular formulation for mid-face and jawline

$460.00

Ellans-L (Long) - 1mL~3 years longevity - premium choice for structural facial rejuvenation

$560.00

Ellans-E (Extra Long) - 1mL~4 years longevity - for experienced patients seeking maximum duration

$680.00

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The only collagen stimulator that delivers immediate volume correction AND progressive regeneration lasting 1-4 years

Ellans is a next-generation injectable filler manufactured by Sinclair Pharma (now part of Huons Group). Unlike conventional HA fillers, Ellans combines a carboxymethylcellulose (CMC) gel carrier - which provides immediate, reversible volume correction - with polycaprolactone (PCL) microspheres that stimulate the body's own collagen production for long-lasting regenerative results. It is the only filler that allows practitioners to precisely tailor longevity - from 1 year (Ellans-S) to 4 years (Ellans-E) - through formulation selection.

Dual action - immediate CMC gel volume + progressive PCL collagen stimulation
4 formulations - precisely tailored longevity from 1 year (S) to 4 years (E)
CE-marked - used by aesthetic practitioners in over 70 countries worldwide

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Huons Sinclair Pharma

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Ellans - Immediate Volume, Progressive Collagen, Tailored Longevity

Ellans represents a genuine advancement in injectable aesthetics. Unlike pure HA fillers that simply replace volume or pure collagen stimulators that require patience for results, Ellans delivers both - simultaneously. Its CMC gel carrier provides instant, visible volume correction at the time of injection, while its PCL microspheres slowly stimulate the body's own neocollagenesis for progressive, long-lasting tissue improvement.

Most remarkably, Ellans is the only injectable filler that allows practitioners to precisely select longevity. With four formulations offering approximately 1, 2, 3, or 4 years of results, Ellans enables tailored treatment planning to suit individual patient preferences, lifestyle, and anatomy - from first-time patients (Ellans-S) to experienced patients seeking maximum duration (Ellans-E).

Why Practitioners Choose Ellans

01Immediate results - CMC gel carrier provides visible correction immediately after injection
02Progressive improvement - PCL microspheres stimulate neocollagenesis over months
03Tailored longevity - four formulations from ~1 year (S) to ~4 years (E)
04PCL is fully biodegradable - absorbed safely by the body over time, leaving only new collagen
05CE-marked - used by aesthetic practitioners in over 70 countries worldwide

Product Specifications

Manufacturer	Sinclair Pharma (Huons Group)
Active Ingredient	Polycaprolactone (PCL) microspheres in CMC carrier gel
Mechanism	Immediate CMC volume + progressive PCL neocollagenesis
Volume	1mL per syringe
Certifications	CE-marked, available in 70+ countries
Formulations	S (~1yr), M (~2yr), L (~3yr), E (~4yr)
Biodegradable	Yes - PCL fully absorbed, CMC gel absorbed within weeks
Price Range	$380.00 - $680.00 / syringe

PCL vs. Other Collagen Stimulators

Ellans (PCL) - Immediate + progressive, tailored longevity 1-4 years, biodegradable

Sculptra (PLLA) - Progressive only (no immediate volume), 2+ years, requires reconstitution

Radiesse (CaHA) - Immediate + stimulatory, ~12-18 months, non-tailorable longevity

HA Fillers - Immediate only, 6-18 months, reversible with hyaluronidase

The Ellans Formulation Range

Ellans-S - ~1 Year

The entry-level formulation. Ideal for first-time Ellans patients, areas requiring shorter-duration correction, or practitioners who prefer a conservative approach with new patients. The CMC gel is absorbed quickly after injection, and the PCL microspheres stimulate collagen for approximately 12 months before being fully biodegraded. $380.00/syringe.

Ellans-M - ~2 Years

The most popular formulation. Offers an excellent balance of longevity, cost-effectiveness, and predictability. Ideal for mid-face volumization, jawline definition, cheek augmentation, and nasolabial fold correction in patients who have experienced Ellans-S or who are confident in their desired outcome. $460.00/syringe.

Ellans-L - ~3 Years

For patients seeking premium longevity and value. Particularly suited to structural facial zones - cheekbones, temples, jawline - where sustained lift and projection are desired over multiple years. Best reserved for patients with established Ellans experience and clear aesthetic goals. $560.00/syringe.

Ellans-E - ~4 Years

Maximum longevity. Reserved for experienced Ellans patients with well-established aesthetic goals who want to minimize the frequency of maintenance treatments. Requires careful patient selection and thorough consent regarding the 4-year duration. $680.00/syringe.

Ideal Candidates for Ellans

Ellans suits patients seeking natural-looking, long-lasting facial volumization with the added benefit of progressive collagen stimulation. Its four formulations make it uniquely adaptable to a wide range of patients - from conservative first-timers to experienced patients wanting years of sustained results.

Best Suited For

+Patients seeking mid-face volumization, cheek projection, or jawline definition
+Patients who want longer-lasting results than conventional HA fillers provide
+Practitioners wanting a dual-action product that delivers immediate and progressive results
+Patients interested in tailored longevity - the ability to choose 1, 2, 3, or 4 years

Contraindications

-Known hypersensitivity to polycaprolactone or carboxymethylcellulose
-Active skin infection or inflammation at the treatment site
-Pregnancy or breastfeeding - safety not established
-Patients with autoimmune diseases or tendency to keloid/hypertrophic scarring
-Ellans is NOT reversible - unlike HA fillers, PCL cannot be dissolved. Patient selection and technique are critical.

See Important Safety Information below.

No. Unlike HA fillers, Ellans cannot be dissolved with hyaluronidase. The PCL microspheres are biodegradable but cannot be removed once injected. This is why careful patient selection, thorough consultation, and precise injection technique are essential. Practitioners must ensure patients fully understand and consent to the selected formulation's longevity.

Both are collagen stimulators, but they differ significantly. Sculptra (PLLA) requires multiple treatment sessions and provides no immediate volume - results develop gradually over 3-6 months. Ellans (PCL) provides immediate volume correction with its CMC carrier gel, alongside progressive collagen stimulation. Ellans also offers four formulations for tailored longevity, whereas Sculptra results last approximately 2 years.

For first-time Ellans patients, Ellans-S (~1 year) or Ellans-M (~2 years) is generally recommended. Starting with a shorter-duration formulation allows both patient and practitioner to assess results and satisfaction before committing to longer-duration options. Ellans-L and Ellans-E are best reserved for experienced patients with established aesthetic goals.

Ellans is primarily indicated for mid-face volumization - cheeks, nasolabial folds, and facial contour. It is also used for jawline definition, chin augmentation, and temple volumization. It should be injected into the deep dermis or subcutaneous tissue using standard filler techniques. It is not indicated for lip augmentation or superficial injections.

Patients see an immediate result from the CMC gel carrier at the time of injection. As the CMC gel is gradually absorbed (over several weeks), the PCL microspheres progressively stimulate collagen production. The final result - fully collagen-supported - typically becomes apparent approximately 3-4 months after treatment and is sustained for the duration selected by the formulation choice.